COVID-19 Evidence Synthesis

The SPOR Evidence Alliance is committed to promoting evidence-informed health policy, practice and service by providing context-sensitive and demand-driven up-to-date scientific evidence to decision-makers. This page showcases knowledge synthesis work being conducted by the Alliance researchers in response to decision-maker needs.

If you  are seeking synthesized evidence to inform decision(s) related to health policy, practice and/or service for COVID-19, please tell us about your research needs by completing the query intake form found here.

We will be making ongoing updates and additions to this page. Stay tuned.


Rapid review on the effects of vaccination in the immunocompromised and those on dialysis Completed

View Findings


Coming soon.

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
National Advisory Committee on Immunization (NACI)
Led by: Paul Moayyedi, McMaster University


Pregnancy related risks associated with COVID-19: A Rapid Review Completed

View Findings


Final Report

Review Data

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Public Health Agency of Canada (PHAC)
Led by: Dr. Ahmed Abou-Setta, Knowledge Synthesis Platform, George and Fay Yee Centre for Healthcare Innovation, University of Manitoba


Rapid Review: What is the Effectiveness, Immunogenicity and Safety of COVID-19 Vaccines in Persons Who Have Had a Prior, Confirmed COVID-19 Infection? Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
National Advisory Committee on Immunization (NACI)
Led by: Dr. Maureen Dobbins, The National Collaborating Centre for Methods and Tools, McMaster University


Surveillance of COVID-19 in Vaccinated Population: A Rapid Review and Environmental Scan Completed

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Health Canada
Led by: Dr. Fiona Clement, The Health Technology Assessment Unit, University of Calgary


Rapid Diagnostic Testing for COVID-19 in a fully vaccinated population: A Rapid Systematic Review Completed

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Health Canada
Led by: Dr. Craig Mitton, Centre for Clinical Epidemiology and Evaluation, Vancouver Coastal Health Research Institute; School of Population and Public Health, University of British Columbia


Care Models for Long COVID: A Rapid Systematic Review Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Alberta Health Services
Led by: Dr. Simon Décary, University of Sherbrooke


Public Health and Health Systems Impacts of SARS-CoV-2 Variants of Concern Rapid Scoping Review Completed

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Alberta Health Services and Public Health Agency of Canada
Led by: Dr. Janet Curran, School of Nursing, Dalhousie University


Transmission characteristics of SARS-CoV-2 variants of concern Completed

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Alberta Health Services and Public Health Agency of Canada
Led by: Dr. Janet Curran, School of Nursing, Dalhousie University


Transmissibility of COVID-19 Among Vaccinated Individuals: Targeted Literature Search Completed

View Findings


Plain Language Summary

Updated Report (May 27, 2021)

Updated Report (March 12, 2021)

First Report (March 2, 2021)

Funded by: Canadian Institutes of Health Research through COVID-END
Knowledge user(s):
Alberta Health Services
Led by: Dr. Fiona Clement, The Health Technology Assessment Unit, University of Calgary


At-home COVID-19 testing: A rapid scoping review Completed

Funded by: Health Canada
Knowledge user(s):
Health Canada and Canadian Institutes of Health Research
Led by: Dr. Meaghan Sim, Nova Scotia Health – Research, Innovation & Discovery


Barriers to COVID-19 testing and testing hesitancy: A rapid scoping review Completed

Funded by: Health Canada
Knowledge user(s):
Health Canada and Canadian Institutes of Health Research
Led by: Dr. Meaghan Sim, Nova Scotia Health – Research, Innovation & Discovery


The implementation of rapid point-of-care testing in non-traditional settings: A rapid review Completed

Funded by: Health Canada
Knowledge user(s):
Health Canada and Canadian Institutes of Health Research
Led by: Dr. Meaghan Sim, Nova Scotia Health – Research, Innovation & Discovery


Preventing the Transmission of COVID-19 in Older Adults Aged 60 Years and Above Living in Long-Term Care: Rapid Review Update Completed

View Findings


Final Report

Funded by: World Health Organization and the Canadian Institutes of Health Research
Knowledge user(s):
World Health Organization
Led by: Dr. Fiona Clement, The Health Technology Assessment Unit, University of Calgary

Related reports and publications:
  1. Rios P, Radhakrishnan A, Williams C, Ramkissoon N, Pham B, Cormack GV, Grossman MR, Muller MP, Straus SE, Tricco AC. Preventing the transmission of COVID-19 and other coronaviruses in older adults aged 60 years and above living in long-term care: a rapid review. Syst Rev. 2020 Sep 25;9(1):218. doi: 10.1186/s13643-020-01486-4. PMID: 32977848.
  2. Rios P, Radhakrishnan A, Thomas SM, Darvesh N, Straus SE, Tricco AC. Preventing respiratory illness in older adults aged 60 years and above living in long-term care: A rapid overview of reviews. medRxiv 2020 Mar 19; doi: https://doi.org/10.1101/2020.03.19.20039081.
  3. Rios P, Radhakrishnan A, Thomas SM, Darvesh N, Straus SE, Tricco AC. Guidelines for preventing respiratory illness in older adults aged 60 years and above living in long-term care: A rapid review of clinical practice guidelines. medRxiv 2020 Mar 19; doi: https://doi.org/10.1101/2020.03.19.20039180.

Effective Models of Provider Care in Long-Term Care Homes: A Rapid Scoping Review Completed

Funded by: Canadian Institutes of Health Research
Knowledge user(s): Royal Society of Canada
Led by: Dr. Brian Hutton, Ottawa Hospital Research Institute


Communication in Disasters Between Health Professionals and Families with Children with Medical complexity or Special Healthcare Needs In progress

View Findings


Coming soon.

Funded by: Canadian Institutes of Health Research
Knowledge user(s): BC Children’s Hospital
Led by: Dr. Craig Mitton, School of Population and Public Health, University of British Columbia


Mitigating the Socioeconomic Impact of Women’s, Children’s and Adolescent’s Health during Pandemics and Epidemics In progress

View Findings


Coming soon.

Funded by: Canadian Institutes of Health Research and World Health Organization
Knowledge user(s): World Health Organization
Led by: Dr. Fiona Clement, The Health Technology Assessment Unit, University of Calgary


Digital Health Interventions for the Prevention, Detection and Management of Mental Health Problems in People with Chronic Diseases Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research
Knowledge user(s): Cliniques Médicales ProActive
Led by: Dr. Marie-Pierre Gagnon and Dr. Annie LeBlanc, Centre de recherche sur les soins et les services de première ligne de l’Université Laval (CERSSPL-UL)


Testing for Asymptomatic COVID-19: A Rapid Systematic Review and Jurisdictional/Healthcare Organizational Scan Completed

View Findings


Coming soon.

Funded by: Canadian Institutes of Health Research
Knowledge user(s):
Ontario Ministry of Health and Long-Term Care
Led by: Dr. Ahmed M. Abou-Setta, George & Fay Yee Centre for Healthcare Innovation, University of Manitoba


Rapid and Point-of-Care Diagnostic Test for SARS-COV-2 (COVID-19): A Rapid Summary Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research
Knowledge user(s):
Ontario Ministry of Health and Long-Term Care
Led by: Dr. Shannon E. Kelly and Dr. George A. Wells, Cardiovascular Research Methods Centre, University of Ottawa Heart Institute


Risk of Acquiring COVID-19 Associated with Singing in a Choir: A Quick Response Report Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research
Knowledge user(s):
Ontario Ministry of Health and Long-Term Care
Led by: Dr. Stephen Bornstein, Newfoundland and Labrador Centre for Applied Health Research, Memorial University of Newfoundland


Preventing the Transmission of Coronavirus (COVID-19) in Older Adults Aged 60 Years and Above Living in Long-Term Care: A Rapid Review Completed

View Findings


Research Brief

Funded by: Canadian Frailty Network
Knowledge user(s):
Canadian Frailty Network
Led by: Dr. Andrea Tricco, Knowledge Translation Program, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Unity Health Toronto


COVID-19 in Children with Brain-Based Developmental Disabilities: A Rapid Review Completed

View Findings


Final Report

Infographic

Funded by: Canadian Institutes of Health Research and CHILD-BRIGHT Network
Knowledge user(s):
CHILD-BRIGHT Network
Led by: Dr. Annie LeBlanc, Centre de recherche sur les soins et les services de première ligne de l’Université Laval (CERSSPL-UL)


Transmission of Acute Respiratory Infections During Aerosol Generating Medical Procedures: Update of 2011 CADTH Systematic Review Completed

View Findings


Final Report

Funded by: Canadian Institutes of Health Research
Knowledge user(s):
Alberta Health Services
Led by: Dr. Fiona Clement, The Health Technology Assessment Unit, University of Calgary


Guidelines for Preventing Respiratory Illness in Older Adults Aged 60 Years and Above Living in Long-Term Care: A Rapid Review of Clinical Practice Guidelines Completed

View Findings


Final Report

Funded by: World Health Organization
Knowledge user(s):
Infection Prevention & Control, Health Emergencies Programme, World Health Organization
Led by: Dr. Andrea Tricco, Knowledge Translation Program, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Unity Health Toronto


Preventing Respiratory Illness in Older Adults Aged 60 Years and Above Living in Long-Term Care: A Rapid Overview of Reviews Completed

View Findings


Final Report

Funded by: World Health Organization
Knowledge user(s):
Infection Prevention & Control, Health Emergencies Programme, World Health Organization
Led by: Dr. Andrea Tricco, Knowledge Translation Program, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Unity Health Toronto