Guideline for Prevention of Rh Alloimmunisation

Antenatal and Postpartum Prevention of Rh Alloimmunisation: A Systematic Review and GRADE Analysis

Project Status:Complete

Knowledge User(s)

Society of Obstetricians and Gynaecologists of Canada

Project Trainee(s)

Alan Michaud, Leila Esmaeilisaraji, Lindsey Sikora


Karen Fung-Kee-Fung

Funding Source(s)

  • Canadian Institutes of Health Research (CIHR) through the Strategy for Patient-Oriented Research (SPOR) Evidence Alliance

Project Objectives

To synthesize and evaluate the certainty of evidence, using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework, for randomised controlled trials and comparative observational studies around the preventive effectiveness of Rh-D immunoglobulin in Rh-negative pregnant or postpartum women at risk of Rh alloimmunisation.

Research Approach

GRADE Analysis, Systematic Review

Project Lead(s)

Brian Hutton

Position: Ottawa Hospital Research Institute, University of Ottawa

Brian Hutton

Ottawa Hospital Research Institute, University of Ottawa